May-Thurner syndrome (MTS), also known as iliac vein compression syndrome or Non Thrombotic Iliac Vein Lesion (NIVL).
The most frequent presentation is chronic venous insufficiency. Patients complain of acute, intermittent, and progressive (activity-related) heaviness and swelling of left lower limb or venous claudication that is relieved with rest and leg elevation.
The progression of the chronic venous insufficiency—manifested as pain, venous claudication, varices, skin hyperpigmentation, and ulceration there by affecting quality of life (QOL).
Many times, patients after standard ablative treatment for varicose veins have increased tightness or discomfort with activity with poor medium- or long-term results and delay medical consultation.
Other less common presentation is acute, spontaneous, and painful leftleg swelling (Deep Vein Thrombosis) with no precipitating cause, or the disease may first present during or after pregnancy and a history of recent use of oral contraceptive pills. May-Thurners Syndrome prevalence is associated in 20% to 50% of cases of left lower-limb Deep Vein Thrombosis.
Noninvasive diagnostic tests include Color venous duplex ultrasound and Cross-sectional imaging: CT/MR venography.
Endo Vascular Treatment of May Thurner’s Syndrome/NIVL
Management depends upon the presence of symptoms, severity, and whether or not DVT is present.
The gold standard for Confirmation of MTS and Intervention is venography plus Intravascular ultrasound.